Until now, bird flu (Avian influenza) are still consuming a lot of attention of the world. Although other diseases such as dengue, tuberculosis, malaria and diarrhea have morbidity and mortality rates are much greater than bird flu, but they are not potentially cause a pandemic. Bird flu pandemic could cause negative impact of extraordinary social, economic and human security. It is estimated that a bird flu pandemic would result in economic losses reached U.S. $ 800 billion and caused the death of 50-160 million people worldwide. However, it is difficult to predict the emergence of bird flu pandemic as the difficulty of estimating the occurrence of earthquakes.
There are 3 of pandemic flu is a world epidemic, the Spanish Flu (1918), caused by H1N1 virus and caused 40 million deaths; Asian Flu (1957), caused by H2N2 virus and caused 4 million deaths; Hong Kong Flu (1968), caused by H3N2 virus and causing 1 million deaths. WHO (2005) states that the bird flu pandemic is different from the flu. Bird flu pandemic may occur in all countries in the world with the spread of patients and deaths and the spread of extensive drug supply is not evenly distributed. This can be a bad influence on economic and social development.

